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Oncogenic State and Cell Identity Combinatorially Dictate the Susceptibility of Cells within Glioma Development Hierarchy to IGF1R Targeting

Glioblastoma is the most malignant cancer in the brain and currently incurable. It is urgent to identify effective targets for this lethal disease. Inhibition of such targets should suppress the growth of cancer cells and, ideally also precancerous cells for early prevention, but minimally affect th...

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Detalles Bibliográficos
Autores principales: Tian, Anhao, Kang, Bo, Li, Baizhou, Qiu, Biying, Jiang, Wenhong, Shao, Fangjie, Gao, Qingqing, Liu, Rui, Cai, Chengwei, Jing, Rui, Wang, Wei, Chen, Pengxiang, Liang, Qinghui, Bao, Lili, Man, Jianghong, Wang, Yan, Shi, Yu, Li, Jin, Yang, Minmin, Wang, Lisha, Zhang, Jianmin, Hippenmeyer, Simon, Zhu, Junming, Bian, Xiuwu, Wang, Ying‐Jie, Liu, Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610337/
https://www.ncbi.nlm.nih.gov/pubmed/33173731
http://dx.doi.org/10.1002/advs.202001724