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Tissue-specific and interferon-inducible expression of non-functional ACE2 through endogenous retroelement co-option

Angiotensin-converting enzyme 2 (ACE2) is an entry receptor for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and a regulator of several physiological processes. ACE2 has recently been proposed to be interferon-inducible, suggesting that SARS-CoV-2 may exploit this phenomenon to enhan...

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Detalles Bibliográficos
Autores principales: Ng, Kevin W., Attig, Jan, Bolland, William, Young, George R., Major, Jack, Wrobel, Antoni G., Gamblin, Steve, Wack, Andreas, Kassiotis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610354/
https://www.ncbi.nlm.nih.gov/pubmed/33077915
http://dx.doi.org/10.1038/s41588-020-00732-8