Photocatalytic proximity labelling of MCL-1 by a BH3 ligand

Ligand-directed protein labelling allows the introduction of diverse chemical functionalities onto proteins without the need for genetically encoded tags. Here we report a method for the rapid labelling of a protein using a ruthenium-bipyridyl (Ru(II)(bpy)(3))-modified peptide designed to mimic an i...

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Detalles Bibliográficos
Autores principales: Beard, Hester A., Hauser, Jacob R., Walko, Martin, George, Rachel M., Wilson, Andrew J., Bon, Robin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610391/
https://www.ncbi.nlm.nih.gov/pubmed/33763603
http://dx.doi.org/10.1038/s42004-019-0235-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610391/
https://www.ncbi.nlm.nih.gov/pubmed/33763603
http://dx.doi.org/10.1038/s42004-019-0235-z

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