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Trehalose limits opportunistic mycobacterial survival during HIV co-infection by reversing HIV-mediated autophagy block

Opportunistic bacterial infections amongst HIV–infected individuals contribute significantly to HIV-associated mortality. The role of HIV-mediated modulation of innate mechanisms like autophagy in promoting opportunistic infections, however, remains obscure. Here we show, HIV reactivation in or infe...

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Detalles Bibliográficos
Autores principales: Sharma, Vartika, Makhdoomi, Muzamil, Singh, Lakshyaveer, Kumar, Purnima, Khan, Nabab, Singh, Sarman, Verma, H N, Luthra, Kalpana, Sarkar, Sovan, Kumar, Dhiraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610453/
https://www.ncbi.nlm.nih.gov/pubmed/32079455
http://dx.doi.org/10.1080/15548627.2020.1725374