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Expanding the antibacterial selectivity of polyether ionophore antibiotics through diversity focused semi-synthesis

Polyether ionophores are complex natural products capable of transporting cations across biological membranes. Many polyether ionophores possess potent antimicrobial activity and a few selected compounds have ability to target aggressive cancer cells. Nevertheless, ionophore function is believed to...

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Detalles Bibliográficos
Autores principales: Lin, Shaoquan, Liu, Han, Svenningsen, Esben B., Wollesen, Malene, Jacobsen, Kristian M., Andersen, Frederikke D., Villameriel, Jaime M., Pedersen, Christine N., Nørby, Peter, Tørring, Thomas, Poulsen, Thomas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610524/
https://www.ncbi.nlm.nih.gov/pubmed/33353970
http://dx.doi.org/10.1038/s41557-020-00601-1