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Expanding the antibacterial selectivity of polyether ionophore antibiotics through diversity focused semi-synthesis
Polyether ionophores are complex natural products capable of transporting cations across biological membranes. Many polyether ionophores possess potent antimicrobial activity and a few selected compounds have ability to target aggressive cancer cells. Nevertheless, ionophore function is believed to...
Autores principales: | Lin, Shaoquan, Liu, Han, Svenningsen, Esben B., Wollesen, Malene, Jacobsen, Kristian M., Andersen, Frederikke D., Villameriel, Jaime M., Pedersen, Christine N., Nørby, Peter, Tørring, Thomas, Poulsen, Thomas B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610524/ https://www.ncbi.nlm.nih.gov/pubmed/33353970 http://dx.doi.org/10.1038/s41557-020-00601-1 |
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