Cargando…
KAT7 is a genetic vulnerability of acute myeloid leukemias driven by MLL rearrangements
Histone acetyltransferases (HATs) catalyze the transfer of an acetyl group from acetyl-CoA to lysine residues of histones and play a central role in transcriptional regulation in diverse biological processes. Dysregulation of HAT activity can lead to human diseases including developmental disorders...
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610570/ https://www.ncbi.nlm.nih.gov/pubmed/32764680 http://dx.doi.org/10.1038/s41375-020-1001-z |