Disruption of the MSL complex inhibits tumor maintenance by exacerbating chromosomal instability

Rewiring of cellular programs in malignant cells generates cancer-specific vulnerabilities. Here, using an unbiased screening strategy aimed at identifying non-essential genes required by tumor cells to sustain unlimited proliferative capacity, we identify the Male-Specific Lethal (MSL) acetyltransf...

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Detalles Bibliográficos
Autores principales: Monserrat, Josep, Torres, Cristina Morales, Richardson, Louise, Wilson, Thomas S., Patel, Harshil, Domart, Marie-Charlotte, Horswell, Stuart, Song, Ok-Ryul, Jiang, Ming, Crawford, Margaret, Bui, Minh, Dalal, Yamini, Scaffidi, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610593/
https://www.ncbi.nlm.nih.gov/pubmed/33837287
http://dx.doi.org/10.1038/s41556-021-00657-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610593/
https://www.ncbi.nlm.nih.gov/pubmed/33837287
http://dx.doi.org/10.1038/s41556-021-00657-2

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