Spatial integration of transcription and splicing in a dedicated compartment sustains monogenic antigen expression in African trypanosomes

Highly selective gene expression is a key requirement for antigenic variation in several pathogens, allowing evasion of host immune responses and maintenance of persistent infections (1). African trypanosomes, parasites that cause lethal diseases in humans and livestock, employ an antigenic variatio...

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Detalles Bibliográficos
Autores principales: Faria, Joana, Luzak, Vanessa, Müller, Laura S.M., Brink, Benedikt G., Hutchinson, Sebastian, Glover, Lucy, Horn, David, Siegel, T. Nicolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610597/
https://www.ncbi.nlm.nih.gov/pubmed/33432154
http://dx.doi.org/10.1038/s41564-020-00833-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610597/
https://www.ncbi.nlm.nih.gov/pubmed/33432154
http://dx.doi.org/10.1038/s41564-020-00833-4

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