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Targeted Perturb-seq enables genome-scale genetic screens in single cells
The transcriptome contains rich information on molecular, cellular, and organismal phenotypes. However, experimental and statistical limitations constrain sensitivity and throughput of genetic screening with single-cell transcriptomics readout. To overcome these limitations, we introduce targeted Pe...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610614/ https://www.ncbi.nlm.nih.gov/pubmed/32483332 http://dx.doi.org/10.1038/s41592-020-0837-5 |