A comprehensive library of human transcription factors for cell fate engineering

Human pluripotent stem cells (hPSCs) offer an unprecedented opportunity to model diverse cell types and tissues. To enable systematic exploration of the programming landscape mediated by transcription factors (TFs), we present the Human TFome, a comprehensive library containing 1,564 TF genes and 1,...

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Detalles Bibliográficos
Autores principales: Ng, Alex H.M., Khoshakhlagh, Parastoo, Arias, Jesus Eduardo Rojo, Pasquini, Giovanni, Wang, Kai, Swiersy, Anka, Shipman, Seth L., Appleton, Evan, Kiaee, Kiavash, Kohman, Richie E., Vernet, Andyna, Dysart, Matthew, Leeper, Kathleen, Saylor, Wren, Huang, Jeremy Y., Graveline, Amanda, Taipale, Jussi, Hill, David E., Vidal, Marc, Melero-Martin, Juan M., Busskamp, Volker, Church, George M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610615/
https://www.ncbi.nlm.nih.gov/pubmed/33257861
http://dx.doi.org/10.1038/s41587-020-0742-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610615/
https://www.ncbi.nlm.nih.gov/pubmed/33257861
http://dx.doi.org/10.1038/s41587-020-0742-6

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