Readfish enables targeted nanopore sequencing of gigabase-sized genomes

Nanopore sequencers can be used to selectively sequence certain DNA molecules in a pool by reversing the voltage across individual nanopores to reject specific sequences, enabling enrichment and depletion to address biological questions. Previously, we achieved this using dynamic time warping to map...

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Detalles Bibliográficos
Autores principales: Payne, Alexander, Holmes, Nadine, Clarke, Thomas, Munro, Rory, Debebe, Bisrat J, Loose, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610616/
https://www.ncbi.nlm.nih.gov/pubmed/33257864
http://dx.doi.org/10.1038/s41587-020-00746-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610616/
https://www.ncbi.nlm.nih.gov/pubmed/33257864
http://dx.doi.org/10.1038/s41587-020-00746-x

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