A first exon termination checkpoint preferentially suppresses extragenic transcription

Interactions between the splicing machinery and RNA Polymerase II (RNA Pol II) increase protein-coding gene transcription. Similarly, exons and splicing signals of enhancer-generated lncRNAs (elncRNAs) augment enhancer activity. However, elncRNAs are inefficiently spliced, suggesting that compared t...

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Detalles Bibliográficos
Autores principales: Austenaa, Liv M.I., Piccolo, Viviana, Russo, Marta, Prosperini, Elena, Polletti, Sara, Polizzese, Danilo, Ghisletti, Serena, Barozzi, Iros, Diaferia, Giuseppe R., Natoli, Gioacchino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610630/
https://www.ncbi.nlm.nih.gov/pubmed/33767452
http://dx.doi.org/10.1038/s41594-021-00572-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610630/
https://www.ncbi.nlm.nih.gov/pubmed/33767452
http://dx.doi.org/10.1038/s41594-021-00572-y

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