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Site-specific covalent labeling of His-tag fused proteins with N-acyl-N-alkyl sulfonamide reagent

The ability to incorporate a desired functionality into proteins of interest in a site-specific manner can provide powerful tools for investigating biological systems and creating therapeutic conjugates. However, there are not any universal methods that can be applied to all proteins, and it is thus...

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Detalles Bibliográficos
Autores principales: Thimaradka, Vikram, Oh, Jae Hoon, Heroven, Christina, Aricescu, A. Radu, Yuzaki, Michisuke, Tamura, Tomonori, Hamachi, Itaru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610637/
https://www.ncbi.nlm.nih.gov/pubmed/33360195
http://dx.doi.org/10.1016/j.bmc.2020.115947