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Structural snapshots of actively transcribing influenza polymerase

Influenza virus RNA-dependent RNA polymerase uses unique mechanisms to transcribe its single-stranded genomic vRNA into mRNA. The polymerase is initially bound to a promoter comprising the partially base-paired 3′ and 5′ extremities of the vRNA. A short, capped primer, ′cap-snatched′ from a nascent...

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Detalles Bibliográficos
Autores principales: Kouba, Tomas, Drncova, Petra, Cusack, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610713/
https://www.ncbi.nlm.nih.gov/pubmed/31160782
http://dx.doi.org/10.1038/s41594-019-0232-z