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ChIP-seq of plasma cell-free nucleosomes identifies gene expression programs of the cells-of-origin
Cell-free DNA in human plasma provides access to molecular information about the pathological processes in the organs or tumors from which it originates. These DNA fragments are derived from fragmented chromatin in dying cells, and retain some of the cell of origin histone modifications. Here, we ap...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610786/ https://www.ncbi.nlm.nih.gov/pubmed/33432199 http://dx.doi.org/10.1038/s41587-020-00775-6 |