ChIP-seq of plasma cell-free nucleosomes identifies gene expression programs of the cells-of-origin

Cell-free DNA in human plasma provides access to molecular information about the pathological processes in the organs or tumors from which it originates. These DNA fragments are derived from fragmented chromatin in dying cells, and retain some of the cell of origin histone modifications. Here, we ap...

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Detalles Bibliográficos
Autores principales: Sadeh, Ronen, Sharkia, Israa, Fialkoff, Gavriel, Rahat, Ayelet, Gutin, Jenia, Chappleboim, Alon, Nitzan, Mor, Fox-Fisher, Ilana, Neiman, Daniel, Meler, Guy, Kamari, Zahala, Yaish, Dayana, Peretz, Tamar, Hubert, Ayala, Cohen, Jonathan E, Salah, Azzam, Temper, Mark, Grinshpun, Albert, Maoz, Myriam, Abu-Gazala, Samir, Ya’acov, Ami Ben, Shteyer, Eyal, Safadi, Rifaat, Kaplan, Tommy, Shemer, Ruth, Planer, David, Galun, Eithan, Glaser, Benjamin, Zick, Aviad, Dor, Yuval, Friedman, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610786/
https://www.ncbi.nlm.nih.gov/pubmed/33432199
http://dx.doi.org/10.1038/s41587-020-00775-6

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