Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection

The interplay between host and pathogen relies heavily on rapid protein synthesis and accurate protein targeting to ensure pathogen destruction. To gain insight into this dynamic interface, we combined click-chemistry with pulsed stable isotope labeling of amino acids in cell culture (pSILAC-AHA) to...

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Detalles Bibliográficos
Autores principales: Selkrig, Joel, Li, Nan, Hausmann, Annika, Mangan, Matthew S. J., Zietek, Matylda, Mateus, André, Bobonis, Jacob, Sueki, Anna, Imamura, Haruna, El Debs, Bachir, Sigismondo, Gianluca, Florea, Bogdan I., Overkleeft, Herman S., Kopitar-Jerala, Natasa, Turk, Boris, Beltrao, Pedro, Savitski, Mikhail, Latz, Eicke, Hardt, Wolf-Dietrich, Krijgsveld, Jeroen, Typas, Athanasios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610801/
https://www.ncbi.nlm.nih.gov/pubmed/32514074
http://dx.doi.org/10.1038/s41564-020-0736-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610801/
https://www.ncbi.nlm.nih.gov/pubmed/32514074
http://dx.doi.org/10.1038/s41564-020-0736-7

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