A map of transcriptional heterogeneity and regulatory variation in human microglia

Microglia, the tissue resident macrophages of the CNS, play critical roles in immune defence, development and homeostasis. However, isolating microglia from humans in large numbers is challenging. Here, we profiled gene expression variation in primary human microglia isolated from 141 patients under...

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Detalles Bibliográficos
Autores principales: Young, Adam MH, Kumasaka, Natsuhiko, Calvert, Fiona, Hammond, Timothy R, Knights, Andrew, Panousis, Nikolaos, Park, Jun Sung, Schwartzentruber, Jeremy, Liu, Jimmy, Kundu, Kousik, Segel, Michael, Murphy, Natalia A, McMurran, Christopher E, Bulstrode, Harry, Correia, Jason, Budohoski, Karol P, Joannides, Alexis, Guilfoyle, Mathew R, Trivedi, Rikin, Kirollos, Ramez, Morris, Robert, Garnett, Matthew R, Timofeev, Ivan, Jalloh, Ibrahim, Holland, Katherine, Mannion, Richard, Mair, Richard, Watts, Colin, Price, Stephen J, Kirkpatrick, Peter J, Santarius, Thomas, Mountjoy, Edward, Ghoussaini, Maya, Soranzo, Nicole, Bayraktar, Omer A., Stevens, Beth, Hutchinson, Peter J, Franklin, Robin JM, Gaffney, Daniel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610960/
https://www.ncbi.nlm.nih.gov/pubmed/34083789
http://dx.doi.org/10.1038/s41588-021-00875-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610960/
https://www.ncbi.nlm.nih.gov/pubmed/34083789
http://dx.doi.org/10.1038/s41588-021-00875-2

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