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A map of transcriptional heterogeneity and regulatory variation in human microglia
Microglia, the tissue resident macrophages of the CNS, play critical roles in immune defence, development and homeostasis. However, isolating microglia from humans in large numbers is challenging. Here, we profiled gene expression variation in primary human microglia isolated from 141 patients under...
Autores principales: | Young, Adam MH, Kumasaka, Natsuhiko, Calvert, Fiona, Hammond, Timothy R, Knights, Andrew, Panousis, Nikolaos, Park, Jun Sung, Schwartzentruber, Jeremy, Liu, Jimmy, Kundu, Kousik, Segel, Michael, Murphy, Natalia A, McMurran, Christopher E, Bulstrode, Harry, Correia, Jason, Budohoski, Karol P, Joannides, Alexis, Guilfoyle, Mathew R, Trivedi, Rikin, Kirollos, Ramez, Morris, Robert, Garnett, Matthew R, Timofeev, Ivan, Jalloh, Ibrahim, Holland, Katherine, Mannion, Richard, Mair, Richard, Watts, Colin, Price, Stephen J, Kirkpatrick, Peter J, Santarius, Thomas, Mountjoy, Edward, Ghoussaini, Maya, Soranzo, Nicole, Bayraktar, Omer A., Stevens, Beth, Hutchinson, Peter J, Franklin, Robin JM, Gaffney, Daniel J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610960/ https://www.ncbi.nlm.nih.gov/pubmed/34083789 http://dx.doi.org/10.1038/s41588-021-00875-2 |
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