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Recent trends in the stereoselective synthesis of (poly)-substituted 2-oxo acids by biocatalyzed aldol reaction
Recently, an increased interest toward enzymatic carboligation was observed, as biocatalytic carbon–carbon bond formation is a common obstacle in retrosynthetic planning. The construction of extended 2-oxoacid frameworks by 2-oxoacid aldolases and enzymes acting as aldolases is a potent tool for syn...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7610986/ https://www.ncbi.nlm.nih.gov/pubmed/34141957 http://dx.doi.org/10.1016/j.cogsc.2021.100476 |