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Virulence of the emerging pathogen, Burkholderia pseudomallei, depends upon the O-linked oligosaccharyltransferase, PglL

AIM: We sought to characterize the contribution of the O-OTase, PglL, to virulence in two Burkholderia spp. by comparing isogenic mutants in Burkholderia pseudomallei with the related species, Burkholderia thailandensis. MATERIALS & METHODS: We utilized an array of in vitro assays in addition to...

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Detalles Bibliográficos
Autores principales: Willcocks, Samuel J, Denman, Carmen, Cia, Felipe, McCarthy, Elizabeth, Cuccui, Jon, Wren, Brendan W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611010/
https://www.ncbi.nlm.nih.gov/pubmed/32271107
http://dx.doi.org/10.2217/fmb-2019-0165