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Multi-particle cryo-EM refinement with M visualizes ribosome-antibiotic complex at 3.5 Å in cells

Cryo-electron microscopy (cryo-EM) enables macromolecular structure determination in vitro and inside cells. In addition to aligning individual particles, accurate registration of sample motion and 3D deformation during exposures are crucial for achieving high resolution reconstructions. Here we des...

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Detalles Bibliográficos
Autores principales: Tegunov, Dimitry, Xue, Liang, Dienemann, Christian, Cramer, Patrick, Mahamid, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611018/
https://www.ncbi.nlm.nih.gov/pubmed/33542511
http://dx.doi.org/10.1038/s41592-020-01054-7