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A single, clinically relevant dose of the GABA(B) agonist baclofen impairs visuomotor learning

The GABA(B) agonist baclofen is taken daily as a treatment for spasticity by millions of stroke, brain injury and multiple sclerosis patients, many of whom are also undergoing motor rehabilitation. However, decreases in GABA are suggested to be a key feature of human motor learning, which raises que...

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Detalles Bibliográficos
Autores principales: Johnstone, Ainslie, Grigoras, Ioana, Petitet, Pierre, Capitão, Liliana P., Stagg, Charlotte J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611062/
https://www.ncbi.nlm.nih.gov/pubmed/33085094
http://dx.doi.org/10.1113/JP280378