oxLDL-Induced Trained Immunity Is Dependent on Mitochondrial Metabolic Reprogramming

Following brief exposure to endogenous atherogenic particles, such as oxidized low-density lipoprotein (oxLDL), monocytes/macrophages can adopt a long-term pro-inflammatory phenotype, which is called trained immunity. This mechanism might contribute to the chronic low-grade inflammation that charact...

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Detalles Bibliográficos
Autores principales: Groh, Laszlo A., Ferreira, Anaisa V., Helder, Leonie, van der Heijden, Charlotte D. C. C., Novakovic, Boris, van de Westerlo, Els, Matzaraki, Vasiliki, Moorlag, Simone J. C. F. M., de Bree, L. Charlotte, Koeken, Valerie A. C. M., Mourits, Vera P., Keating, Samuel T., van Puffelen, Jelmer H., Hoischen, Alexander, Joosten, Leo A. B., Netea, Mihai G., Koopman, Werner J. H., Riksen, Niels P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611242/
https://www.ncbi.nlm.nih.gov/pubmed/34267957
http://dx.doi.org/10.20900/immunometab20210025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611242/
https://www.ncbi.nlm.nih.gov/pubmed/34267957
http://dx.doi.org/10.20900/immunometab20210025

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