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Single-cell CUT&Tag profiles histone modifications and transcription factors in complex tissues
In contrast to single-cell approaches for measuring gene expression and DNA accessibility, single-cell methods for analyzing histone modifications are limited by low sensitivity and throughput. Here we combine the CUT&Tag technology, developed to measure bulk histone modifications, with droplet-...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611252/ https://www.ncbi.nlm.nih.gov/pubmed/33846645 http://dx.doi.org/10.1038/s41587-021-00869-9 |