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Chemoenzymatic Production of Enantiocomplementary 2-Substituted 3-Hydroxycarboxylic Acids from L-α-Amino Acids

A two-enzyme cascade reaction plus in situ oxidative decarboxylation for the transformation of readily available canonical and non-canonical L-α-amino acids into 2-substituted 3-hydroxy-carboxylic acid derivatives is described. The biocatalytic cascade consisted of an oxidative deamination of L-α-am...

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Detalles Bibliográficos
Autores principales: Pickl, Mathias, Marín-Valls, Roser, Joglar, Jesús, Bujons, Jordi, Clapés, Pere
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611260/
https://www.ncbi.nlm.nih.gov/pubmed/34276272
http://dx.doi.org/10.1002/adsc.202100145