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Sex-based dimorphism of anticancer immune response and molecular mechanisms of immune evasion

PURPOSE: We previously demonstrated that sex influences response to immune-checkpoint inhibitors. Here we investigate sex-based differences in the molecular mechanisms of anticancer immune-response and immune evasion in patients with NSCLC. EXPERIMENTAL DESIGN: We analyzed a) transcriptome-data of 2...

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Detalles Bibliográficos
Autores principales: Conforti, Fabio, Pala, Laura, Pagan, Eleonora, Bagnardi, Vincenzo, De Pas, Tommaso, Queirolo, Paola, Pennacchioli, Elisabetta, Catania, Chiara, Cocorocchio, Emilia, Ferrucci, Pier Francesco, Saponara, Maristella, Orsolini, Gianmarco, Zagami, Paola, Nicoló, Eleonora, De Marinis, Filippo, Tortora, Giampaolo, Bria, Emilio, Minucci, Saverio, Joffe, Hadine, Veronesi, Paolo, Wargo, Jennifer, Rosenthal, Rachel, Swanton, Charles, Mantovani, Alberto, Gelber, Richard D., Viale, Giuseppe, Goldhirsch, Aron, Giaccone, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611463/
https://www.ncbi.nlm.nih.gov/pubmed/34016641
http://dx.doi.org/10.1158/1078-0432.CCR-21-0136