Interplay between γδT-Cell Metabolism and Tumour Microenvironment Offers Opportunities for Therapeutic Intervention

Solid tumour targeting using adoptive cell therapy has failed to reproduce the spectacular clinical successes seen with chimeric antigen receptor T cell therapies and B cell malignancies. Low in glucose, oxygen, pH and populated with suppressive cells, the solid tumour microenvironment (TME) remains...

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Detalles Bibliográficos
Autores principales: Barisa, Marta, Fowler, Daniel, Fisher, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611484/
https://www.ncbi.nlm.nih.gov/pubmed/34394978
http://dx.doi.org/10.20900/immunometab20210026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611484/
https://www.ncbi.nlm.nih.gov/pubmed/34394978
http://dx.doi.org/10.20900/immunometab20210026

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