Cargando…

Tolcapone in Obsessive Compulsive disorder: A Randomized Double-Blind Placebo-Controlled Crossover Trial

OBJECTIVE: Despite the availability of evidence-based treatments for obsessive-compulsive disorder (OCD), not all patients experience sufficient benefit or are able to tolerate them. Tolcapone is a catechol-o-methyl-transferase (COMT) enzyme inhibitor that augments cortical dopaminergic transmission...

Descripción completa

Detalles Bibliográficos
Autores principales: Grant, Jon E., Hook, Roxanne, Valle, Stephanie, Chesivoir, Eve, Chamberlain, Samuel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611531/
https://www.ncbi.nlm.nih.gov/pubmed/34310432
http://dx.doi.org/10.1097/YIC.0000000000000368