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Tolcapone in Obsessive Compulsive disorder: A Randomized Double-Blind Placebo-Controlled Crossover Trial
OBJECTIVE: Despite the availability of evidence-based treatments for obsessive-compulsive disorder (OCD), not all patients experience sufficient benefit or are able to tolerate them. Tolcapone is a catechol-o-methyl-transferase (COMT) enzyme inhibitor that augments cortical dopaminergic transmission...
Autores principales: | Grant, Jon E., Hook, Roxanne, Valle, Stephanie, Chesivoir, Eve, Chamberlain, Samuel R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611531/ https://www.ncbi.nlm.nih.gov/pubmed/34310432 http://dx.doi.org/10.1097/YIC.0000000000000368 |
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