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Identification of Tse8 as a Type VI secretion system toxin from Pseudomonas aeruginosa that targets the bacterial transamidosome to inhibit protein synthesis in prey cells

The Type VI secretion system (T6SS) is a bacterial nanomachine which delivers toxic effectors to kill competitors or subvert some of their key functions. Here we use transposon directed insertion-site sequencing (TraDIS) to identify T6SS toxins associated with the H1-T6SS, one of the three T6SS mach...

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Detalles Bibliográficos
Autores principales: Nolan, Laura M., Cain, Amy K., Clamens, Thomas, Furniss, R. Christopher D., Manoli, Eleni, Sainz-Polo, Maria A., Dougan, Gordon, Albesa-Jové, David, Parkhill, Julian, Mavridou, Despoina A.I., Filloux, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611593/
https://www.ncbi.nlm.nih.gov/pubmed/34413503
http://dx.doi.org/10.1038/s41564-021-00950-8