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With a grain of salt: Sodium elevation and metabolic remodelling in heart failure
Elevated intracellular Na (Na(i)) and metabolic impairment are interrelated pathophysiological features of the failing heart (HF). There have been a number of studies showing that myocardial sodium elevation subtly affects mitochondrial function. During contraction, mitochondrial calcium (Ca(mito))...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611640/ https://www.ncbi.nlm.nih.gov/pubmed/34371034 http://dx.doi.org/10.1016/j.yjmcc.2021.08.003 |