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With a grain of salt: Sodium elevation and metabolic remodelling in heart failure

Elevated intracellular Na (Na(i)) and metabolic impairment are interrelated pathophysiological features of the failing heart (HF). There have been a number of studies showing that myocardial sodium elevation subtly affects mitochondrial function. During contraction, mitochondrial calcium (Ca(mito))...

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Detalles Bibliográficos
Autores principales: Aksentijević, Dunja, Shattock, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611640/
https://www.ncbi.nlm.nih.gov/pubmed/34371034
http://dx.doi.org/10.1016/j.yjmcc.2021.08.003