Reduced glucocorticoid production rate, decreased 5α-reductase activity and adipose tissue insulin sensitization following weight loss

OBJECTIVE: The epidemic of obesity, insulin resistance and type 2 diabetes has heightened the need to understand mechanisms that contribute to their pathogenesis. Increased endogenous glucocorticoid (GC) production has been implicated based upon parallels with Cushing’s syndrome. We have assessed th...

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Detalles Bibliográficos
Autores principales: Tomlinson, Jeremy W, Finney, Joanne, Hughes, Beverly A, Hughes, Susan V, Stewart, Paul M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611651/
https://www.ncbi.nlm.nih.gov/pubmed/18340018
http://dx.doi.org/10.2337/db08-0094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611651/
https://www.ncbi.nlm.nih.gov/pubmed/18340018
http://dx.doi.org/10.2337/db08-0094

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