Conformation Sensitive Targeting of Lipid Nanoparticles for RNA Therapeutics

The successful in vivo implementation of gene expression modulation strategies relies on effective, non-immunogenic delivery vehicles. Lipid nanoparticles (LNPs) are one of the most advanced, non-viral clinically approved nucleic-acid delivery systems. Yet, LNPs accumulate naturally in liver cells u...

Descripción completa

Detalles Bibliográficos
Autores principales: Dammes, Niels, Goldsmith, Meir, Ramishetti, Srinivas, Dearling, Jason L. J., Veiga, Nuphar, Packard, Alan B., Peer, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611664/
https://www.ncbi.nlm.nih.gov/pubmed/34140675
http://dx.doi.org/10.1038/s41565-021-00928-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611664/
https://www.ncbi.nlm.nih.gov/pubmed/34140675
http://dx.doi.org/10.1038/s41565-021-00928-x

Ejemplares similares