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Conformation Sensitive Targeting of Lipid Nanoparticles for RNA Therapeutics

The successful in vivo implementation of gene expression modulation strategies relies on effective, non-immunogenic delivery vehicles. Lipid nanoparticles (LNPs) are one of the most advanced, non-viral clinically approved nucleic-acid delivery systems. Yet, LNPs accumulate naturally in liver cells u...

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Detalles Bibliográficos
Autores principales:	Dammes, Niels, Goldsmith, Meir, Ramishetti, Srinivas, Dearling, Jason L. J., Veiga, Nuphar, Packard, Alan B., Peer, Dan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611664/ https://www.ncbi.nlm.nih.gov/pubmed/34140675 http://dx.doi.org/10.1038/s41565-021-00928-x

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