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Deep learning enables fast and dense single-molecule localization with high accuracy

Single-molecule localization microscopy (SMLM) has had remarkable success in imaging cellular structures with nanometer resolution, but standard analysis algorithms necessitate the activation of only single isolated emitters which limits imaging speed and labeling density. Here, we overcome this maj...

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Detalles Bibliográficos
Autores principales: Speiser, Artur, Müller, Lucas-Raphael, Hoess, Philipp, Matti, Ulf, Obara, Christopher J., Legant, Wesley R., Kreshuk, Anna, Macke, Jakob H., Ries, Jonas, Turaga, Srinivas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611669/
https://www.ncbi.nlm.nih.gov/pubmed/34480155
http://dx.doi.org/10.1038/s41592-021-01236-x