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Self-repair protects microtubules from their destruction by molecular motors

Microtubule instability stems from the low energy of tubulin dimer interactions, which sets the growing polymer close to its disassembly conditions. Molecular motors use ATP hydrolysis to produce mechanical work and move on microtubules. This raises the possibility that the mechanical work produced...

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Detalles Bibliográficos
Autores principales: Triclin, Sarah, Inoue, Daisuke, Gaillard, Jérémie, Htet, Zaw Min, DeSantis, Morgan E., Portran, Didier, Derivery, Emmanuel, Aumeier, Charlotte, Schaedel, Laura, John, Karin, Leterrier, Christophe, Reck-Peterson, Samara L., Blanchoin, Laurent, Théry, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611741/
https://www.ncbi.nlm.nih.gov/pubmed/33479528
http://dx.doi.org/10.1038/s41563-020-00905-0