An atlas of mitochondrial DNA genotype-phenotype associations in the UK Biobank

Mitochondrial genome (mtDNA) variation in common diseases has been under-explored, partly due to a lack of genotype calling and quality control procedures. Developing an at-scale workflow for mtDNA variant analyses, we show correlations between nuclear and mitochondrial genomic structures within sub...

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Detalles Bibliográficos
Autores principales: Yonova-Doing, Ekaterina, Calabrese, Claudia, Gomez-Duran, Aurora, Schon, Katherine, Wei, Wei, Karthikeyan, Savita, Chinnery, Patrick F., Howson, Joanna M. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611844/
https://www.ncbi.nlm.nih.gov/pubmed/34002094
http://dx.doi.org/10.1038/s41588-021-00868-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611844/
https://www.ncbi.nlm.nih.gov/pubmed/34002094
http://dx.doi.org/10.1038/s41588-021-00868-1

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