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Phenotypic Characterization of Leukemia-Initiating Stem Cells in Chronic Myelomonocytic Leukemia

Chronic myelomonocytic leukemia (CMML) is a stem cell-derived neoplasm characterized by dysplasia, uncontrolled expansion of monocytes and a substantial risk to transform to secondary acute myeloid leukemia (sAML). So far, little is known about CMML-initiating cells. We found that leukemic stem cell...

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Detalles Bibliográficos
Autores principales: Eisenwort, Gregor, Sadovnik, Irina, Keller, Alexandra, Ivanov, Daniel, Peter, Barbara, Berger, Daniela, Stefanzl, Gabriele, Bauer, Karin, Slavnitsch, Katharina, Greiner, Georg, Gleixner, Karoline V., Sperr, Wolfgang R., Willmann, Michael, Sill, Heinz, Bettelheim, Peter, Geissler, Klaus, Deininger, Michael, Rülicke, Thomas, Valent, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611912/
https://www.ncbi.nlm.nih.gov/pubmed/33785864
http://dx.doi.org/10.1038/s41375-021-01227-z