Effects of apolipoprotein B on lifespan and risks of major diseases including type 2 diabetes: a mendelian randomisation analysis using outcomes in first-degree relatives

BACKGROUND: Apolipoprotein B (apoB) is emerging as the crucial lipoprotein trait for the role of lipoprotein lipids in the aetiology of coronary heart disease. In this study, we evaluated the effects of genetically predicted apoB on outcomes in first-degree relatives. METHODS: Data on lipoprotein li...

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Detalles Bibliográficos
Autores principales: Richardson, Tom G, Wang, Qin, Sanderson, Eleanor, Mahajan, Anubha, McCarthy, Mark I, Frayling, Timothy M, Ala-Korpela, Mika, Sniderman, Allan, Smith, George Davey, Holmes, Michael V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611924/
https://www.ncbi.nlm.nih.gov/pubmed/34729547
http://dx.doi.org/10.1016/S2666-7568(21)00086-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611924/
https://www.ncbi.nlm.nih.gov/pubmed/34729547
http://dx.doi.org/10.1016/S2666-7568(21)00086-6

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