Reciprocal Transcription Factor Networks Govern Tissue-Resident ILC3 Subset Function and Identity

Innate Lymphoid Cells (ILCs) are guardians of mucosal immunity, yet the transcriptional networks that support their function remain poorly understood. We employed inducible combinatorial deletion of key transcription factors (TFs) required for ILC development (RORγt, RORα and T-bet) to determine the...

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Detalles Bibliográficos
Autores principales: Fiancette, Rémi, Finlay, Conor, Willis, Claire, Bevington, Sarah L., Soley, Jake, Ng, Sky T.H., Baker, Syed Murtuza, Andrews, Simon, Hepworth, Matthew R., Withers, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611981/
https://www.ncbi.nlm.nih.gov/pubmed/34556884
http://dx.doi.org/10.1038/s41590-021-01024-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611981/
https://www.ncbi.nlm.nih.gov/pubmed/34556884
http://dx.doi.org/10.1038/s41590-021-01024-x

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