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Investigation of the Interplay between Circulating Lipids and IGF-I and Relevance to Breast Cancer Risk: An Observational and Mendelian Randomization Study

BACKGROUND: Circulating lipids and insulin-like growth factor 1 (IGF-I) have been reliably associated with breast cancer. Observational studies suggest an interplay between lipids and IGF-I, however, whether these relationships are causal and if pathways from these phenotypes to breast cancer overla...

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Detalles Bibliográficos
Autores principales: Tan, Vanessa Y., Bull, Caroline J., Biernacka, Kalina M., Teumer, Alexander, Richardson, Tom G., Sanderson, Eleanor, Corbin, Laura J., Dudding, Tom, Qi, Qibin, Kaplan, Robert C., Rotter, Jerome I., Friedrich, Nele, Völker, Uwe, Mayerle, Julia, Perks, Claire M., Holly, Jeff M.P., Timpson, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612074/
https://www.ncbi.nlm.nih.gov/pubmed/34583967
http://dx.doi.org/10.1158/1055-9965.EPI-21-0315