Molecular basis of a redox switch: molecular dynamics simulations and surface plasmon resonance provide insight into reduced and oxidised angiotensinogen

Angiotensinogen fine-tunes the tightly controlled activity of the renin-angiotensin system by modulating the release of angiotensin peptides that control blood pressure. One mechanism by which this modulation is achieved is via angiotensinogen’s Cys18–Cys138 disulfide bond that acts as a redox switc...

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Detalles Bibliográficos
Autores principales: Crowther, Jennifer M., Gilmour, Letitia H., Porebski, Benjamin T., Heath, Sarah G., Pattinson, Neil R., Owen, Maurice C., Fredericks, Rayleen, Buckle, Ashley M., Fee, Conan J., Göbl, Christoph, Dobson, Renwick C. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612104/
https://www.ncbi.nlm.nih.gov/pubmed/34424335
http://dx.doi.org/10.1042/BCJ20210476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612104/
https://www.ncbi.nlm.nih.gov/pubmed/34424335
http://dx.doi.org/10.1042/BCJ20210476

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