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The transcription factor EGR2 is indispensable for tissue-specific imprinting of alveolar macrophages in health and tissue repair( # )

Alveolar macrophages are the most abundant macrophages in the healthy lung where they play key roles in homeostasis and immune surveillance against air-borne pathogens. Tissue-specific differentiation and survival of alveolar macrophages relies on niche-derived factors, such as granulocyte-macrophag...

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Detalles Bibliográficos
Autores principales: McCowan, Jack, Fercoq, Frédéric, Kirkwood, Phoebe M., T’Jonck, Wouter, Hegarty, Lizi M., Mawer, Connar M., Cunningham, Richard, Mirchandani, Ananda S., Hoy, Anna, Humphries, Duncan C., Jones, Gareth-Rhys, Hansen, Carsten G., Hirani, Nik, Jenkins, Stephen J., Henri, Sandrine, Malissen, Bernard, Walmsley, Sarah R., Dockrell, David H., Saunders, Philippa T. K., Carlin, Leo M., Bain, Calum C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612216/
https://www.ncbi.nlm.nih.gov/pubmed/34797692
http://dx.doi.org/10.1126/sciimmunol.abj2132