Quantifying Efficiency Gains of Innovative Designs of Two-Arm Vaccine Trials for COVID-19 Using an Epidemic Simulation Model

Clinical trials of a vaccine during an epidemic face particular challenges, such as the pressure to identify an effective vaccine quickly to control the epidemic, and the effect that time-space-varying infection incidence has on the power of a trial. We illustrate how the operating characteristics o...

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Detalles Bibliográficos
Autores principales: Johnson, Rob, Jackson, Chris, Presanis, Anne, Villar, Sofia S., De Angelis, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612285/
https://www.ncbi.nlm.nih.gov/pubmed/35096276
http://dx.doi.org/10.1080/19466315.2021.1939774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612285/
https://www.ncbi.nlm.nih.gov/pubmed/35096276
http://dx.doi.org/10.1080/19466315.2021.1939774

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