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Accurate error control in high-dimensional association testing using conditional false discovery rates

High-dimensional hypothesis testing is ubiquitous in the biomedical sciences, and informative covariates may be employed to improve power. The conditional false discovery rate (cFDR) is a widely used approach suited to the setting where the covariate is a set of p-values for the equivalent hypothese...

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Detalles Bibliográficos
Autores principales: Liley, James, Wallace, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612315/
https://www.ncbi.nlm.nih.gov/pubmed/33682201
http://dx.doi.org/10.1002/bimj.201900254