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Red Blood Cell Cryopreservation with Minimal Post-Thaw Lysis Enabled by a Synergistic Combination of a Cryoprotecting Polyampholyte with DMSO/Trehalose

[Image: see text] From trauma wards to chemotherapy, red blood cells are essential in modern medicine. Current methods to bank red blood cells typically use glycerol (40 wt %) as a cryoprotective agent. Although highly effective, the deglycerolization process, post-thaw, is time-consuming and result...

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Detalles Bibliográficos
Autores principales: Murray, Alex, Congdon, Thomas R., Tomás, Ruben M. F., Kilbride, Peter, Gibson, Matthew I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612374/
https://www.ncbi.nlm.nih.gov/pubmed/34097399
http://dx.doi.org/10.1021/acs.biomac.1c00599