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Analysis of ligand binding and resulting conformational changes in pyrophosphatase NUDT9
Nudix hydrolase 9 (NUDT9) is a member of the nucleoside linked to another moiety X (NUDIX) protein superfamily, which hydrolyses a broad spectrum of organic pyrophosphates from metabolic processes. ADP‐ribose (ADPR) has been the only known endogenous substrate accepted by NUDT9 so far. The Ca(2+)‐pe...
Autores principales: | Gattkowski, Ellen, Rutherford, Trevor J., Möckl, Franziska, Bauche, Andreas, Sander, Simon, Fliegert, Ralf, Tidow, Henning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612441/ https://www.ncbi.nlm.nih.gov/pubmed/34189846 http://dx.doi.org/10.1111/febs.16097 |
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