Local Treatment of a Pediatric Osteosarcoma Model with a 4-1BBL Armed Oncolytic Adenovirus Results in an Antitumor Effect and Leads to Immune Memory

Osteosarcoma is an aggressive bone tumor occurring primarily in pediatric patients. Despite years of intensive research, the outcomes of patients with metastatic disease or those who do not respond to therapy have remained poor and have not changed in the last 30 years. Oncolytic virotherapy is beco...

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Detalles Bibliográficos
Autores principales: Martinez-Velez, Naiara, Laspidea, Virginia, Zalacain, Marta, Labiano, Sara, García-Moure, Marc, Puigdelloses, Montse, Marrodan, Lucía, Gonzalez-Huarriz, Marisol, Herrador, Guillermo, de la Nava, Daniel, Ausejo-Mauleon, Iker, Fueyo, Juan, Gomez-Manzano, Candelaria, Patiño-García, Ana, Alonso, Marta M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Models and Technologies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612474/
https://www.ncbi.nlm.nih.gov/pubmed/34965961
http://dx.doi.org/10.1158/1535-7163.MCT-21-0565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612474/
https://www.ncbi.nlm.nih.gov/pubmed/34965961
http://dx.doi.org/10.1158/1535-7163.MCT-21-0565

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